Expression of DCAF10 in cancer - Summary - The Human Protein Atlas

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DCAF10

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	DCAF10
Gene description	DDB1 and CUL4 associated factor 10
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA024160
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA024160

GENE INFORMATION
Gene name	DCAF10 (HGNC Symbol)
Synonyms	FLJ23201, MGC10765, WDR32
Description	DDB1 and CUL4 associated factor 10 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	p13.2
Chromosome location (bp)	37800502 - 37867666
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000122741 (version 83.38)
Entrez gene	79269
UniProt	Q5QP82 (UniProt - Evidence at protein level)
neXtProt	NX_Q5QP82
Antibodypedia	DCAF10 antibodies

PROTEIN BROWSER

DCAF10-001	DCAF10-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DCAF10-001 ENSP00000366953 ENST00000377724	Q5QP82 [Direct mapping] DDB1- and CUL4-associated factor 10 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016567 [protein ubiquitination] GO:0080008 [Cul4-RING E3 ubiquitin ligase complex] Show all	559 aa 60.6 kDa	No	0
DCAF10-201 ENSP00000242323 ENST00000242323	A0A0A0MQT4 [Direct mapping] DDB1- and CUL4-associated factor 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	386 aa 43.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.