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Cancer tissues showed moderate to strong nuclear immunoreactivity. Several renal cancers were weakly stained or negative.
GENE INFORMATION
Gene name
NEUROG3 (HGNC Symbol)
Synonyms
Atoh5, bHLHa7, Math4B, ngn3
Description
Neurogenin 3 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).[provided by RefSeq, May 2010]