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RAP2C

GENERAL INFORMATION

Gene name

 RAP2C

Gene description

 RAP2C, member of RAS oncogene family

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RAP2C (HGNC Symbol)

Synonyms

 DKFZp313B211

Description

 RAP2C, member of RAS oncogene family (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. This protein has been reported to activate in vitro transcriptional activity of the serum response element. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]

Chromosome

 X

Cytoband

 q26.2

Chromosome location (bp)

 132203024 - 132219480

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000123728 (version 83.38)

Entrez gene

 57826

UniProt

 Q9Y3L5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y3L5

Antibodypedia

 RAP2C antibodies

PROTEIN BROWSER
RAP2C-001
RAP2C-002
RAP2C-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RAP2C-001
ENSP00000340274
ENST00000342983
Q9Y3L5 [Direct mapping]
Ras-related protein Rap-2c
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003713 [transcription coactivator activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0019003 [GDP binding]
GO:0030336 [negative regulation of cell migration]
GO:0031954 [positive regulation of protein autophosphorylation]
GO:0032486 [Rap protein signal transduction]
GO:0044291 [cell-cell contact zone]
GO:0055037 [recycling endosome]
GO:0055038 [recycling endosome membrane]
GO:0061097 [regulation of protein tyrosine kinase activity]
GO:0070062 [extracellular exosome]
GO:0090557 [establishment of endothelial intestinal barrier]
GO:1903506 [regulation of nucleic acid-templated transcription]
Show all
 183 aa
20.7 kDa 		No 0
RAP2C-002
ENSP00000359911
ENST00000370874
Q9Y3L5 [Direct mapping]
Ras-related protein Rap-2c
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003713 [transcription coactivator activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0019003 [GDP binding]
GO:0030336 [negative regulation of cell migration]
GO:0031954 [positive regulation of protein autophosphorylation]
GO:0032486 [Rap protein signal transduction]
GO:0044291 [cell-cell contact zone]
GO:0055038 [recycling endosome membrane]
GO:0061097 [regulation of protein tyrosine kinase activity]
GO:0070062 [extracellular exosome]
GO:0090557 [establishment of endothelial intestinal barrier]
GO:1903506 [regulation of nucleic acid-templated transcription]
Show all
 183 aa
20.7 kDa 		No 0
RAP2C-201
ENSP00000484870
ENST00000620646
A0A087X2C3 [Direct mapping]
RAP2C, member of RAS oncogene family, isoform CRA_b; Ras-related protein Rap-2c
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
Show all
 117 aa
13.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.