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RAB38

GENERAL INFORMATION

Gene name

 RAB38

Gene description

 RAB38, member RAS oncogene family

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Cell line enhanced (HaCaT, hTCEpi, SK-MEL-30)
HPA (normal tissue):Tissue enhanced (skin)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 RAB38 (HGNC Symbol)

Synonyms

 NY-MEL-1

Description

 RAB38, member RAS oncogene family (HGNC Symbol)

Entrez gene summary

Chromosome

 11

Cytoband

 q14.2

Chromosome location (bp)

 88113242 - 88175467

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000123892 (version 83.38)

Entrez gene

 23682

UniProt

 P57729 (UniProt - Evidence at protein level)

neXtProt

 NX_P57729

Antibodypedia

 RAB38 antibodies

PROTEIN BROWSER
RAB38-001
RAB38-002
RAB38-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RAB38-001
ENSP00000243662
ENST00000243662
P57729 [Direct mapping]
Ras-related protein Rab-38
A0A024R191 [Target identity:100%; Query identity:100%]
RAB38, member RAS oncogene family, isoform CRA_a
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0006913 [nucleocytoplasmic transport]
GO:0006996 [organelle organization]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0030670 [phagocytic vesicle membrane]
GO:0030742 [GTP-dependent protein binding]
GO:0031982 [vesicle]
GO:0032482 [Rab protein signal transduction]
GO:0035646 [endosome to melanosome transport]
GO:0035650 [AP-1 adaptor complex binding]
GO:0035651 [AP-3 adaptor complex binding]
GO:0036461 [BLOC-2 complex binding]
GO:0042470 [melanosome]
GO:0045335 [phagocytic vesicle]
GO:0060155 [platelet dense granule organization]
GO:0072657 [protein localization to membrane]
GO:0090383 [phagosome acidification]
GO:1903232 [melanosome assembly]
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 211 aa
23.7 kDa 		No 0
RAB38-002
ENSP00000433317
ENST00000526372
H0YDB7 [Direct mapping]
Ras-related protein Rab-38
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005802 [trans-Golgi network]
GO:0006886 [intracellular protein transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0032482 [Rab protein signal transduction]
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 210 aa
22.9 kDa 		No 0
RAB38-003
ENSP00000435340
ENST00000531138
H0YEA4 [Direct mapping]
Ras-related protein Rab-38
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005802 [trans-Golgi network]
GO:0006886 [intracellular protein transport]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0032482 [Rab protein signal transduction]
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 89 aa
10.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.