Expression of DAW1 in cancer - Summary - The Human Protein Atlas

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DAW1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	DAW1
Gene description	Dynein assembly factor with WDR repeat domains 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (HUVEC TERT2, U-2197)
HPA (normal tissue):	Group enriched (fallopian tube, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ciliary expression in fallopian tube and respiratory epithelium.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 1 antibody. HPA046118
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA046118

GENE INFORMATION
Gene name	DAW1 (HGNC Symbol)
Synonyms	FLJ25955, ODA16, WDR69
Description	Dynein assembly factor with WDR repeat domains 1 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q36.3
Chromosome location (bp)	227871054 - 227924344
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000123977 (version 83.38)
Entrez gene	164781
UniProt	Q8N136 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N136
Antibodypedia	DAW1 antibodies

PROTEIN BROWSER

DAW1-001	DAW1-002	DAW1-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DAW1-001 ENSP00000311899 ENST00000309931	Q8N136 [Direct mapping] Dynein assembly factor with WDR repeat domains 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005929 [cilium] GO:0007368 [determination of left/right symmetry] GO:0007507 [heart development] Show all	415 aa 45.8 kDa	No	0
DAW1-002 ENSP00000362770 ENST00000373666	C9JBF9 [Direct mapping] Dynein assembly factor with WDR repeat domains 1; WD repeat domain 69, isoform CRA_c Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	369 aa 40.5 kDa	No	0
DAW1-003 ENSP00000394853 ENST00000440997	C9JP90 [Direct mapping] Dynein assembly factor with WDR repeat domains 1 Show all	Predicted intracellular proteins Show all		71 aa 8.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.