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Secreted protein, tissue location of RNA and protein might differ and correlation is complex. Antibody staining in cells/structures not annotated, view images.
Several cases of colorectal and ovarian cancers along with few prostate, breast, lung, skin, urothelial, pancreatic, stomach and liver cancers displayed moderate, granular cytoplasmic positivity. Remaining cancers were weakly stained or negative.
GENE INFORMATION
Gene name
IL17C (HGNC Symbol)
Synonyms
CX2, IL-17C, IL-21, MGC126884, MGC138401
Description
Interleukin 17C (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq, Jul 2008]