Expression of OARD1 in cancer - Summary - The Human Protein Atlas

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OARD1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	OARD1
Gene description	O-acyl-ADP-ribose deacylase 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	13
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA029036
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA029036

GENE INFORMATION
Gene name	OARD1 (HGNC Symbol)
Synonyms	C6orf130, dJ34B21.3, MGC19570, TARG1
Description	O-acyl-ADP-ribose deacylase 1 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p21.1
Chromosome location (bp)	41033627 - 41097787
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000124596 (version 83.38)
Entrez gene	221443
UniProt	Q9Y530 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y530
Antibodypedia	OARD1 antibodies

PROTEIN BROWSER

OARD1-001	OARD1-002	OARD1-003	OARD1-005	OARD1-008	OARD1-009	OARD1-010	OARD1-011	OARD1-012	OARD1-013	OARD1-014	OARD1-015	OARD1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OARD1-001 ENSP00000420484 ENST00000479950	Q9Y530 [Direct mapping] O-acetyl-ADP-ribose deacetylase 1 A0A024RCY9 [Target identity:100%; Query identity:100%] Chromosome 6 open reading frame 130, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001883 [purine nucleoside binding] GO:0005515 [protein binding] GO:0019213 [deacetylase activity] GO:0042278 [purine nucleoside metabolic process] Show all	152 aa 17 kDa	No	0
OARD1-002 ENSP00000420193 ENST00000463088	Q9Y530 [Direct mapping] O-acetyl-ADP-ribose deacetylase 1 A0A024RCY9 [Target identity:100%; Query identity:100%] Chromosome 6 open reading frame 130, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001883 [purine nucleoside binding] GO:0005515 [protein binding] GO:0019213 [deacetylase activity] GO:0042278 [purine nucleoside metabolic process] Show all	152 aa 17 kDa	No	0
OARD1-003 ENSP00000362247 ENST00000373154	C9J5P1 [Direct mapping] Chromosome 6 open reading frame 130, isoform CRA_a; O-acetyl-ADP-ribose deacetylase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		86 aa 9.7 kDa	No	0
OARD1-005 ENSP00000416829 ENST00000424266	Q9Y530 [Direct mapping] O-acetyl-ADP-ribose deacetylase 1 A0A024RCY9 [Target identity:100%; Query identity:100%] Chromosome 6 open reading frame 130, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001883 [purine nucleoside binding] GO:0005515 [protein binding] GO:0019213 [deacetylase activity] GO:0042278 [purine nucleoside metabolic process] Show all	152 aa 17 kDa	No	0
OARD1-008 ENSP00000419175 ENST00000486443	C9JXC3 [Direct mapping] O-acetyl-ADP-ribose deacetylase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		113 aa 12.8 kDa	No	0
OARD1-009 ENSP00000420601 ENST00000468811	Q9Y530 [Direct mapping] O-acetyl-ADP-ribose deacetylase 1 A0A024RCY9 [Target identity:100%; Query identity:100%] Chromosome 6 open reading frame 130, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001883 [purine nucleoside binding] GO:0005515 [protein binding] GO:0019213 [deacetylase activity] GO:0042278 [purine nucleoside metabolic process] Show all	152 aa 17 kDa	No	0
OARD1-010 ENSP00000417333 ENST00000471367	C9IZY1 [Direct mapping] O-acetyl-ADP-ribose deacetylase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		88 aa 9.9 kDa	No	0
OARD1-011 ENSP00000418966 ENST00000469104	C9IZY1 [Direct mapping] O-acetyl-ADP-ribose deacetylase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		88 aa 9.9 kDa	No	0
OARD1-012 ENSP00000418098 ENST00000482515	C9JA90 [Direct mapping] O-acetyl-ADP-ribose deacetylase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		77 aa 8.5 kDa	No	0
OARD1-013 ENSP00000419875 ENST00000464633	C9JA90 [Direct mapping] O-acetyl-ADP-ribose deacetylase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		77 aa 8.5 kDa	No	0
OARD1-014 ENSP00000420414 ENST00000488238	C9JNE2 [Direct mapping] O-acetyl-ADP-ribose deacetylase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		131 aa 14.7 kDa	No	0
OARD1-015 ENSP00000418400 ENST00000480585	C9J5P1 [Direct mapping] Chromosome 6 open reading frame 130, isoform CRA_a; O-acetyl-ADP-ribose deacetylase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		86 aa 9.7 kDa	No	0
OARD1-201 ENSP00000487484 ENST00000628419	C9J5P1 [Direct mapping] Chromosome 6 open reading frame 130, isoform CRA_a; O-acetyl-ADP-ribose deacetylase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		86 aa 9.7 kDa	No	0

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The Human Protein Atlas

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