Moderate to strong nuclear positivity was displayed in several cases of lung and testis cancer. Most remaining cancer tissues were weakly stained or negative.
OPN5 (HGNC Symbol)
dJ402H5.1, neuropsin, TMEM13
Opsin 5 (HGNC Symbol)
Entrez gene summary
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]