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SCGB2A1

GENERAL INFORMATION

Gene name

 SCGB2A1

Gene description

 Secretoglobin, family 2A, member 1

Protein class

 Cancer-related genes
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (cervix, uterine, epididymis)
GTEx:Tissue enhanced (cervix, uterine, fallopian tube)
FANTOM5:Tissue enhanced (epididymis)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression mainly in uterine and epididymal glands.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Supported based on 1 antibody.
HPA034584
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Cervix, uterine

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (cervix, uterine, epididymis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cervix, uterine, fallopian tube)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (epididymis)

GENE INFORMATION

Gene name

 SCGB2A1 (HGNC Symbol)

Synonyms

 LPHC, MGB2, MGC71973, UGB3

Description

 Secretoglobin, family 2A, member 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 11

Cytoband

 q12.3

Chromosome location (bp)

 62208668 - 62213939

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000124939 (version 83.38)

Entrez gene

 4246

UniProt

 O75556 (UniProt - Evidence at protein level)

neXtProt

 NX_O75556

Antibodypedia

 SCGB2A1 antibodies

PROTEIN BROWSER
SCGB2A1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SCGB2A1-001
ENSP00000244930
ENST00000244930
O75556 [Direct mapping]
Mammaglobin-B
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Ezkurdia et al 2014)
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GO:0005615 [extracellular space]
GO:0030521 [androgen receptor signaling pathway]
GO:0046982 [protein heterodimerization activity]
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 95 aa
10.9 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.