Expression of C16orf70 in cancer - Summary - The Human Protein Atlas

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C16orf70

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C16orf70
Gene description	Chromosome 16 open reading frame 70
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA041131 , HPA041214
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041131	HPA041214

GENE INFORMATION
Gene name	C16orf70 (HGNC Symbol)
Synonyms	C16orf6, FLJ12076, lin-10, LIN10
Description	Chromosome 16 open reading frame 70 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q22.1
Chromosome location (bp)	67109958 - 67148539
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000125149 (version 83.38)
Entrez gene	80262
UniProt	Q9BSU1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BSU1
Antibodypedia	C16orf70 antibodies

PROTEIN BROWSER

C16orf70-001	C16orf70-002	C16orf70-009	C16orf70-010	C16orf70-012	C16orf70-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C16orf70-001 ENSP00000219139 ENST00000219139	Q9BSU1 [Direct mapping] UPF0183 protein C16orf70 A0A024R6W4 [Target identity:100%; Query identity:100%] Lin-10 homolog (C. elegans), isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	422 aa 47.5 kDa	No	0
C16orf70-002 ENSP00000455182 ENST00000569600	Q9BSU1 [Direct mapping] UPF0183 protein C16orf70 A0A024R6W4 [Target identity:100%; Query identity:100%] Lin-10 homolog (C. elegans), isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	422 aa 47.5 kDa	No	0
C16orf70-009 ENSP00000456154 ENST00000566026	H3BRA5 [Direct mapping] UPF0183 protein C16orf70 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		165 aa 18.6 kDa	No	0
C16orf70-010 ENSP00000456549 ENST00000569914	H3BS58 [Direct mapping] UPF0183 protein C16orf70 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		222 aa 24.5 kDa	No	0
C16orf70-012 ENSP00000456688 ENST00000563853	H3BSG0 [Direct mapping] UPF0183 protein C16orf70 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		320 aa 36 kDa	No	0
C16orf70-013 ENSP00000464242 ENST00000569277	J3QRI8 [Direct mapping] UPF0183 protein C16orf70 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		98 aa 10.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.