Expression of ARMC7 in cancer - Summary - The Human Protein Atlas

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ARMC7

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ARMC7
Gene description	Armadillo repeat containing 7
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in all tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA024229
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable), renal cancer (favourable) and cervical cancer (favourable).
Liver cancer p<0.001 Renal cancer p<0.001 Cervical cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA024229

GENE INFORMATION
Gene name	ARMC7 (HGNC Symbol)
Synonyms	FLJ22160
Description	Armadillo repeat containing 7 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q25.1
Chromosome location (bp)	75109952 - 75130265
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000125449 (version 83.38)
Entrez gene	79637
UniProt	Q9H6L4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H6L4
Antibodypedia	ARMC7 antibodies

PROTEIN BROWSER

ARMC7-001	ARMC7-002	ARMC7-004	ARMC7-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARMC7-001 ENSP00000245543 ENST00000245543	Q9H6L4 [Direct mapping] Armadillo repeat-containing protein 7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	198 aa 21.9 kDa	No	0
ARMC7-002 ENSP00000462962 ENST00000581078	Q9H6L4 [Direct mapping] Armadillo repeat-containing protein 7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	103 aa 11.4 kDa	No	0
ARMC7-004 ENSP00000462642 ENST00000582136	J3KST7 [Direct mapping] Armadillo repeat containing 7, isoform CRA_c; Armadillo repeat-containing protein 7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] Show all	82 aa 9.2 kDa	No	0
ARMC7-006 ENSP00000462939 ENST00000584947	J3KTE5 [Direct mapping] Armadillo repeat containing 7, isoform CRA_d; Armadillo repeat-containing protein 7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] Show all	101 aa 11.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.