Expression of MSTO1 in cancer - Summary - The Human Protein Atlas

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MSTO1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MSTO1
Gene description	Misato 1, mitochondrial distribution and morphology regulator
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA005899 , HPA005914
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and liver cancer (unfavourable).
Renal cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA005899	HPA005914

GENE INFORMATION
Gene name	MSTO1 (HGNC Symbol)
Synonyms	FLJ10504, LST005, misato, MST
Description	Misato 1, mitochondrial distribution and morphology regulator (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q22
Chromosome location (bp)	155610205 - 155614967
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000125459 (version 83.38)
Entrez gene	55154
UniProt	Q9BUK6 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BUK6
Antibodypedia	MSTO1 antibodies

PROTEIN BROWSER

MSTO1-001	MSTO1-003	MSTO1-018

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MSTO1-001 ENSP00000245564 ENST00000245564	Q9BUK6 [Direct mapping] Protein misato homolog 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003924 [GTPase activity] GO:0005737 [cytoplasm] GO:0005741 [mitochondrial outer membrane] GO:0007005 [mitochondrion organization] GO:0008152 [metabolic process] GO:0048311 [mitochondrion distribution] Show all	570 aa 61.8 kDa	No	0
MSTO1-003 ENSP00000357325 ENST00000368341	Q9BUK6 [Direct mapping] Protein misato homolog 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003924 [GTPase activity] GO:0005737 [cytoplasm] GO:0005741 [mitochondrial outer membrane] GO:0007005 [mitochondrion organization] GO:0008152 [metabolic process] GO:0048311 [mitochondrion distribution] Show all	524 aa 56.9 kDa	No	0
MSTO1-018 ENSP00000476693 ENST00000462250	V9GYF2 [Direct mapping] Protein misato homolog 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		78 aa 8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.