Tissue expression of DDX31 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	DDX31
Gene description	DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	DDX31 (HGNC Symbol)
Synonyms	FLJ13633, FLJ14578, FLJ23349, PPP1R25
Description	DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 (HGNC Symbol)
Entrez gene summary	DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
Chromosome	9
Cytoband	q34.13
Chromosome location (bp)	132592997 - 132670401
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000125485 (version 83.38)
Entrez gene	64794
UniProt	Q9H8H2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H8H2
Antibodypedia	DDX31 antibodies

PROTEIN BROWSER

DDX31-001	DDX31-003	DDX31-004	DDX31-006	DDX31-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DDX31-001 ENSP00000361232 ENST00000372159	Q9H8H2 [Direct mapping] Probable ATP-dependent RNA helicase DDX31 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0004004 [ATP-dependent RNA helicase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005730 [nucleolus] GO:0005794 [Golgi apparatus] GO:0010501 [RNA secondary structure unwinding] GO:0042254 [ribosome biogenesis] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] Show all	851 aa 94.1 kDa	No	0
DDX31-003 ENSP00000310539 ENST00000310532	Q9H8H2 [Direct mapping] Probable ATP-dependent RNA helicase DDX31 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0004004 [ATP-dependent RNA helicase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005730 [nucleolus] GO:0005794 [Golgi apparatus] GO:0010501 [RNA secondary structure unwinding] GO:0042254 [ribosome biogenesis] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] Show all	585 aa 64.1 kDa	No	0
DDX31-004 ENSP00000479697 ENST00000480876	Q9H8H2 [Direct mapping] Probable ATP-dependent RNA helicase DDX31 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0004004 [ATP-dependent RNA helicase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005730 [nucleolus] GO:0005794 [Golgi apparatus] GO:0010501 [RNA secondary structure unwinding] GO:0042254 [ribosome biogenesis] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] Show all	319 aa 34.6 kDa	No	0
DDX31-006 ENSP00000387730 ENST00000438527	F8WAJ0 [Direct mapping] Probable ATP-dependent RNA helicase DDX31 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0004004 [ATP-dependent RNA helicase activity] GO:0005524 [ATP binding] GO:0005730 [nucleolus] GO:0005794 [Golgi apparatus] GO:0010501 [RNA secondary structure unwinding] GO:0043231 [intracellular membrane-bounded organelle] Show all	746 aa 83.5 kDa	No	0
DDX31-201 ENSP00000361226 ENST00000372153	Q9H8H2 [Direct mapping] Probable ATP-dependent RNA helicase DDX31 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0004004 [ATP-dependent RNA helicase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005730 [nucleolus] GO:0005794 [Golgi apparatus] GO:0010501 [RNA secondary structure unwinding] GO:0042254 [ribosome biogenesis] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] Show all	851 aa 94.1 kDa	No	0