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SRMS

GENERAL INFORMATION

Gene name

 SRMS

Gene description

 Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (CAPAN-2, MCF7, RT4)
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
CAB044668 , CAB044669
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Ovarian cancer

STAINING SUMMARY
CAB044668
CAB044669

GENE INFORMATION

Gene name

 SRMS (HGNC Symbol)

Synonyms

 C20orf148, dJ697K14.1, SRM

Description

 Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites (HGNC Symbol)

Entrez gene summary

Chromosome

 20

Cytoband

 q13.33

Chromosome location (bp)

 63540810 - 63547504

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000125508 (version 83.38)

Entrez gene

 6725

UniProt

 Q9H3Y6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H3Y6

Antibodypedia

 SRMS antibodies

PROTEIN BROWSER
SRMS-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SRMS-001
ENSP00000217188
ENST00000217188
Q9H3Y6 [Direct mapping]
Tyrosine-protein kinase Srms
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   Tyr protein kinases
   SPOCTOPUS predicted membrane proteins
   Phobius predicted secreted proteins
Predicted intracellular proteins
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GO:0004672 [protein kinase activity]
GO:0004713 [protein tyrosine kinase activity]
GO:0004715 [non-membrane spanning protein tyrosine kinase activity]
GO:0005102 [receptor binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0007169 [transmembrane receptor protein tyrosine kinase signaling pathway]
GO:0016477 [cell migration]
GO:0030036 [actin cytoskeleton organization]
GO:0030154 [cell differentiation]
GO:0031234 [extrinsic component of cytoplasmic side of plasma membrane]
GO:0038083 [peptidyl-tyrosine autophosphorylation]
GO:0042127 [regulation of cell proliferation]
GO:0045087 [innate immune response]
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 488 aa
54.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.