Tissue expression of CSTL1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CSTL1
Gene description	Cystatin-like 1
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	CSTL1 (HGNC Symbol)
Synonyms	CTES1, dJ322G13.4
Description	Cystatin-like 1 (HGNC Symbol)
Entrez gene summary	The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located at the telomeric end of the cystatin locus and encodes a type 2 cystatin-like protein. The specific function of this protein has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	20
Cytoband	p11.21
Chromosome location (bp)	23439685 - 23444930
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000125823 (version 83.38)
Entrez gene	128817
UniProt	Q9H114 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H114
Antibodypedia	CSTL1 antibodies

PROTEIN BROWSER

CSTL1-001	CSTL1-201	CSTL1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CSTL1-001 ENSP00000246020 ENST00000246020	Q9H114 [Direct mapping] Cystatin-like 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004869 [cysteine-type endopeptidase inhibitor activity] GO:0005576 [extracellular region] GO:0010951 [negative regulation of endopeptidase activity] Show all	145 aa 17 kDa	Yes	0
CSTL1-201 ENSP00000344907 ENST00000347397	Q9H114 [Direct mapping] Cystatin-like 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004869 [cysteine-type endopeptidase inhibitor activity] GO:0005576 [extracellular region] GO:0010951 [negative regulation of endopeptidase activity] Show all	145 aa 17 kDa	Yes	0
CSTL1-202 ENSP00000477757 ENST00000619238	A0A087WTC5 [Direct mapping] Cystatin-like 1 Show all	Predicted intracellular proteins Show all	GO:0004869 [cysteine-type endopeptidase inhibitor activity] GO:0010951 [negative regulation of endopeptidase activity] Show all	37 aa 4.5 kDa	No	0