Expression of FAM83C in cancer - Summary - The Human Protein Atlas

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FAM83C

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM83C
Gene description	Family with sequence similarity 83, member C
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (head and neck cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (esophagus, skin)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA049978 , CAB034227
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (head and neck cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA049978	CAB034227

GENE INFORMATION
Gene name	FAM83C (HGNC Symbol)
Synonyms	C20orf128, dJ614O4.7
Description	Family with sequence similarity 83, member C (HGNC Symbol)
Entrez gene summary
Chromosome	20
Cytoband	q11.22
Chromosome location (bp)	35285731 - 35292401
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000125998 (version 83.38)
Entrez gene	128876
UniProt	Q9BQN1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BQN1
Antibodypedia	FAM83C antibodies

PROTEIN BROWSER

FAM83C-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM83C-001 ENSP00000363529 ENST00000374408	Q9BQN1 [Direct mapping] Protein FAM83C Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Show all	GO:0019901 [protein kinase binding] Show all	747 aa 81.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.