Tissue expression of CEP250 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CEP250
Gene description	Centrosomal protein 250kDa
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	CEP250 (HGNC Symbol)
Synonyms	C-NAP1, CEP2
Description	Centrosomal protein 250kDa (HGNC Symbol)
Entrez gene summary	This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. [provided by RefSeq, Jun 2009]
Chromosome	20
Cytoband	q11.22
Chromosome location (bp)	35455164 - 35519280
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000126001 (version 83.38)
Entrez gene	11190
UniProt	Q9BV73 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BV73
Antibodypedia	CEP250 antibodies

PROTEIN BROWSER

CEP250-001	CEP250-002	CEP250-003	CEP250-006	CEP250-010	CEP250-011	CEP250-012	CEP250-014

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CEP250-001 ENSP00000380661 ENST00000397527	Q9BV73 [Direct mapping] Centrosome-associated protein CEP250 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000278 [mitotic cell cycle] GO:0005515 [protein binding] GO:0005813 [centrosome] GO:0005814 [centriole] GO:0005815 [microtubule organizing center] GO:0005829 [cytosol] GO:0005929 [cilium] GO:0006996 [organelle organization] GO:0008022 [protein C-terminus binding] GO:0008104 [protein localization] GO:0010457 [centriole-centriole cohesion] GO:0019901 [protein kinase binding] GO:0019904 [protein domain specific binding] GO:0030997 [regulation of centriole-centriole cohesion] GO:0031616 [spindle pole centrosome] GO:0033365 [protein localization to organelle] GO:0035058 [nonmotile primary cilium assembly] GO:0043234 [protein complex] GO:0048471 [perinuclear region of cytoplasm] GO:0070062 [extracellular exosome] Show all	2442 aa 281.1 kDa	No	0
CEP250-002 ENSP00000398747 ENST00000446710	Q5JWS5 [Direct mapping] Centrosomal protein 250kDa; Centrosome-associated protein CEP250 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005814 [centriole] Show all	164 aa 19.4 kDa	No	0
CEP250-003 ENSP00000414651 ENST00000420564	Q5JWS6 [Direct mapping] Centrosomal protein 250kDa; Centrosome-associated protein CEP250 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005814 [centriole] Show all	114 aa 13.3 kDa	No	0
CEP250-006 ENSP00000380658 ENST00000397524	A6PVI9 [Direct mapping] Centrosomal protein 250kDa; Centrosome-associated protein CEP250 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005814 [centriole] Show all	339 aa 39.4 kDa	No	0
CEP250-010 ENSP00000400200 ENST00000425096	H0Y5R2 [Direct mapping] Centrosome-associated protein CEP250 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005814 [centriole] Show all	210 aa 22.6 kDa	No	0
CEP250-011 ENSP00000395992 ENST00000422671	H7C0P0 [Direct mapping] Centrosome-associated protein CEP250 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005813 [centrosome] GO:0005814 [centriole] Show all	877 aa 101.6 kDa	No	0
CEP250-012 ENSP00000413827 ENST00000425934	E7ETF9 [Direct mapping] Centrosome-associated protein CEP250 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005814 [centriole] Show all	684 aa 78.6 kDa	No	0
CEP250-014 ENSP00000482323 ENST00000621352	A0A087WZ34 [Direct mapping] Centrosome-associated protein CEP250 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		34 aa 3.7 kDa	No	0