Expression of FRMD8 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

FRMD8

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FRMD8
Gene description	FERM domain containing 8
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA002861
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA002861

GENE INFORMATION
Gene name	FRMD8 (HGNC Symbol)
Synonyms	FKSG44, FLJ90369
Description	FERM domain containing 8 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q13.1
Chromosome location (bp)	65386599 - 65413525
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000126391 (version 83.38)
Entrez gene	83786
UniProt	Q9BZ67 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BZ67
Antibodypedia	FRMD8 antibodies

PROTEIN BROWSER

FRMD8-001	FRMD8-002	FRMD8-003	FRMD8-004	FRMD8-005	FRMD8-008	FRMD8-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FRMD8-001 ENSP00000319726 ENST00000317568	Q9BZ67 [Direct mapping] FERM domain-containing protein 8 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005856 [cytoskeleton] Show all	464 aa 51.2 kDa	No	0
FRMD8-002 ENSP00000348270 ENST00000355991	Q9BZ67 [Direct mapping] FERM domain-containing protein 8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005856 [cytoskeleton] Show all	408 aa 45.1 kDa	No	0
FRMD8-003 ENSP00000433479 ENST00000531296	Q8N4M4 [Direct mapping] FERM domain-containing protein 8; FRMD8 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		66 aa 6.9 kDa	No	0
FRMD8-004 ENSP00000392111 ENST00000416776	Q9BZ67 [Direct mapping] FERM domain-containing protein 8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005856 [cytoskeleton] Show all	430 aa 47.2 kDa	No	0
FRMD8-005 ENSP00000434274 ENST00000525156	E9PRA3 [Direct mapping] FERM domain-containing protein 8 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005856 [cytoskeleton] Show all	90 aa 9.5 kDa	No	0
FRMD8-008 ENSP00000435991 ENST00000526201	E9PRP1 [Direct mapping] FERM domain-containing protein 8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005856 [cytoskeleton] Show all	155 aa 17.2 kDa	No	0
FRMD8-009 ENSP00000435913 ENST00000533782	E9PS62 [Direct mapping] FERM domain-containing protein 8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005856 [cytoskeleton] Show all	184 aa 20.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.