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STATH

GENERAL INFORMATION

Gene name

 STATH

Gene description

 Statherin

Protein class

 Plasma proteins
Predicted secreted proteins
Transporters

Predicted localization

 Secreted

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Group enriched (head and neck cancer, lung cancer)
HPA (cell line):Not detected
HPA (normal tissue):Tissue enriched (salivary gland)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression as well as extracellular positivity in salivary gland.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA044569
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Group enriched (head and neck cancer, lung cancer)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA044569

GENE INFORMATION

Gene name

 STATH (HGNC Symbol)

Synonyms

 STR

Description

 Statherin (HGNC Symbol)

Entrez gene summary

Chromosome

 4

Cytoband

 q13.3

Chromosome location (bp)

 69995930 - 70002570

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000126549 (version 83.38)

Entrez gene

 6779

UniProt

 P02808 (UniProt - Evidence at protein level)

neXtProt

 NX_P02808

Antibodypedia

 STATH antibodies

PROTEIN BROWSER
STATH-001
STATH-003
STATH-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
STATH-001
ENSP00000246895
ENST00000246895
P02808 [Direct mapping]
Statherin
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Transporters
   Transporter channels and pores
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0001503 [ossification]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0030197 [extracellular matrix constituent, lubricant activity]
GO:0030345 [structural constituent of tooth enamel]
GO:0030500 [regulation of bone mineralization]
GO:0030502 [negative regulation of bone mineralization]
GO:0031214 [biomineral tissue development]
GO:0042742 [defense response to bacterium]
GO:0046541 [saliva secretion]
GO:0046848 [hydroxyapatite binding]
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 62 aa
7.3 kDa 		Yes 0
STATH-003
ENSP00000370448
ENST00000381060
P02808 [Direct mapping]
Statherin
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Transporters
   Transporter channels and pores
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001503 [ossification]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0030197 [extracellular matrix constituent, lubricant activity]
GO:0030345 [structural constituent of tooth enamel]
GO:0030500 [regulation of bone mineralization]
GO:0030502 [negative regulation of bone mineralization]
GO:0031214 [biomineral tissue development]
GO:0042742 [defense response to bacterium]
GO:0046541 [saliva secretion]
GO:0046848 [hydroxyapatite binding]
Show all
 52 aa
6.1 kDa 		Yes 0
STATH-201
ENSP00000484341
ENST00000615994
P02808 [Direct mapping]
Statherin
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Transporters
   Transporter channels and pores
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001503 [ossification]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0030197 [extracellular matrix constituent, lubricant activity]
GO:0030345 [structural constituent of tooth enamel]
GO:0030500 [regulation of bone mineralization]
GO:0030502 [negative regulation of bone mineralization]
GO:0031214 [biomineral tissue development]
GO:0042742 [defense response to bacterium]
GO:0046541 [saliva secretion]
GO:0046848 [hydroxyapatite binding]
Show all
 62 aa
7.3 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.