Cell atlas - SLC10A3 - The Human Protein Atlas

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SLC10A3

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Intermediate filaments

Human cell
	Intermediate Filaments

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GENERAL INFORMATION
Gene name	SLC10A3
Gene description	Solute carrier family 10, member 3
Protein class	Predicted membrane proteins Predicted secreted proteins Transporters
Predicted localization	Membrane,Secreted
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the intermediate filaments.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Intermediate filaments (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA021656
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the intermediate filaments.

Main location

Intermediate filaments (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA021656	U-2 OS	Intermediate filaments
	HPA021656	U-251 MG	No staining

GENE INFORMATION
Gene name	SLC10A3 (HGNC Symbol)
Synonyms	DXS253E, P3
Description	Solute carrier family 10, member 3 (HGNC Symbol)
Entrez gene summary	This gene maps to a GC-rich region of the X chromosome and was identified by its proximity to a CpG island. It is thought to be a housekeeping gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2008]
Chromosome	X
Cytoband	q28
Chromosome location (bp)	154487306 - 154490690
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000126903 (version 83.38)
Entrez gene	8273
UniProt	P09131 (UniProt - Evidence at transcript level)
neXtProt	NX_P09131
Antibodypedia	SLC10A3 antibodies

PROTEIN BROWSER

SLC10A3-001	SLC10A3-002	SLC10A3-003	SLC10A3-004	SLC10A3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC10A3-001 ENSP00000358663 ENST00000369649	P09131 [Direct mapping] P3 protein Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Show all	GO:0005887 [integral component of plasma membrane] GO:0008508 [bile acid:sodium symporter activity] GO:0015721 [bile acid and bile salt transport] GO:0016020 [membrane] GO:0055085 [transmembrane transport] Show all	448 aa 47.5 kDa	Yes	8
SLC10A3-002 ENSP00000377212 ENST00000393587	P09131 [Direct mapping] P3 protein Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Show all	GO:0005887 [integral component of plasma membrane] GO:0008508 [bile acid:sodium symporter activity] GO:0015721 [bile acid and bile salt transport] GO:0016020 [membrane] GO:0055085 [transmembrane transport] Show all	477 aa 50.3 kDa	Yes	8
SLC10A3-003 ENSP00000395702 ENST00000453912	Q5HY78 [Direct mapping] P3 protein Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005887 [integral component of plasma membrane] GO:0008508 [bile acid:sodium symporter activity] GO:0015721 [bile acid and bile salt transport] GO:0055085 [transmembrane transport] Show all	218 aa 22.8 kDa	Yes	0
SLC10A3-004 ENSP00000377211 ENST00000393586	A0A0A0MS43 [Direct mapping] P3 protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0005887 [integral component of plasma membrane] GO:0008508 [bile acid:sodium symporter activity] GO:0015721 [bile acid and bile salt transport] GO:0016020 [membrane] GO:0055085 [transmembrane transport] Show all	532 aa 55.9 kDa	No	7
SLC10A3-201 ENSP00000263512 ENST00000263512	P09131 [Direct mapping] P3 protein Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Show all	GO:0005887 [integral component of plasma membrane] GO:0008508 [bile acid:sodium symporter activity] GO:0010033 [response to organic substance] GO:0015721 [bile acid and bile salt transport] GO:0016020 [membrane] GO:0032526 [response to retinoic acid] GO:0055085 [transmembrane transport] Show all	477 aa 50.3 kDa	Yes	8

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.