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RAB3IP

GENERAL INFORMATION

Gene name

 RAB3IP

Gene description

 RAB3A interacting protein

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 12
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Expressed in all
HPA (normal tissue):Tissue enhanced (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in several different tissue types.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA039794
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA039794

GENE INFORMATION

Gene name

 RAB3IP (HGNC Symbol)

Synonyms

 FLJ22548, RABIN3, RABIN8

Description

 RAB3A interacting protein (HGNC Symbol)

Entrez gene summary

Chromosome

 12

Cytoband

 q15

Chromosome location (bp)

 69738681 - 69823204

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000127328 (version 83.38)

Entrez gene

 117177

UniProt

 Q96QF0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96QF0

Antibodypedia

 RAB3IP antibodies

PROTEIN BROWSER
«
RAB3IP-001
RAB3IP-002
RAB3IP-003
RAB3IP-004
RAB3IP-006
RAB3IP-008
RAB3IP-011
RAB3IP-012
RAB3IP-014
RAB3IP-015
RAB3IP-016
RAB3IP-017
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RAB3IP-001
ENSP00000447300
ENST00000550536
Q96QF0 [Direct mapping]
Rab-3A-interacting protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0006612 [protein targeting to membrane]
GO:0006893 [Golgi to plasma membrane transport]
GO:0006996 [organelle organization]
GO:0017112 [Rab guanyl-nucleotide exchange factor activity]
GO:0030027 [lamellipodium]
GO:0033365 [protein localization to organelle]
GO:0036064 [ciliary basal body]
GO:0042384 [cilium assembly]
GO:0043547 [positive regulation of GTPase activity]
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 476 aa
53 kDa 		No 0
RAB3IP-002
ENSP00000355381
ENST00000362025
Q96QF0 [Direct mapping]
Rab-3A-interacting protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0006612 [protein targeting to membrane]
GO:0006893 [Golgi to plasma membrane transport]
GO:0006996 [organelle organization]
GO:0017112 [Rab guanyl-nucleotide exchange factor activity]
GO:0030027 [lamellipodium]
GO:0033365 [protein localization to organelle]
GO:0036064 [ciliary basal body]
GO:0042384 [cilium assembly]
GO:0043547 [positive regulation of GTPase activity]
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 411 aa
45.2 kDa 		No 0
RAB3IP-003
ENSP00000247833
ENST00000247833
Q96QF0 [Direct mapping]
Rab-3A-interacting protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0006612 [protein targeting to membrane]
GO:0006893 [Golgi to plasma membrane transport]
GO:0006996 [organelle organization]
GO:0017112 [Rab guanyl-nucleotide exchange factor activity]
GO:0030027 [lamellipodium]
GO:0033365 [protein localization to organelle]
GO:0036064 [ciliary basal body]
GO:0042384 [cilium assembly]
GO:0043547 [positive regulation of GTPase activity]
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 460 aa
51.2 kDa 		No 0
RAB3IP-004
ENSP00000419216
ENST00000483530
Q96QF0 [Direct mapping]
Rab-3A-interacting protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0006612 [protein targeting to membrane]
GO:0006893 [Golgi to plasma membrane transport]
GO:0006996 [organelle organization]
GO:0017112 [Rab guanyl-nucleotide exchange factor activity]
GO:0030027 [lamellipodium]
GO:0033365 [protein localization to organelle]
GO:0036064 [ciliary basal body]
GO:0042384 [cilium assembly]
GO:0043547 [positive regulation of GTPase activity]
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 395 aa
43.4 kDa 		No 0
RAB3IP-006
ENSP00000368092
ENST00000378815
Q96QF0 [Direct mapping]
Rab-3A-interacting protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0006612 [protein targeting to membrane]
GO:0006893 [Golgi to plasma membrane transport]
GO:0006996 [organelle organization]
GO:0017112 [Rab guanyl-nucleotide exchange factor activity]
GO:0030027 [lamellipodium]
GO:0033365 [protein localization to organelle]
GO:0036064 [ciliary basal body]
GO:0042384 [cilium assembly]
GO:0043547 [positive regulation of GTPase activity]
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 315 aa
34.3 kDa 		No 0
RAB3IP-008
ENSP00000448773
ENST00000551641
Q96QF0 [Direct mapping]
Rab-3A-interacting protein
Show all
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0006612 [protein targeting to membrane]
GO:0006893 [Golgi to plasma membrane transport]
GO:0006996 [organelle organization]
GO:0017112 [Rab guanyl-nucleotide exchange factor activity]
GO:0030027 [lamellipodium]
GO:0033365 [protein localization to organelle]
GO:0036064 [ciliary basal body]
GO:0042384 [cilium assembly]
GO:0043547 [positive regulation of GTPase activity]
Show all
 254 aa
28.6 kDa 		No 0
RAB3IP-011
ENSP00000448027
ENST00000553099
Q96QF0 [Direct mapping]
Rab-3A-interacting protein
Show all
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0006612 [protein targeting to membrane]
GO:0006893 [Golgi to plasma membrane transport]
GO:0006996 [organelle organization]
GO:0017112 [Rab guanyl-nucleotide exchange factor activity]
GO:0030027 [lamellipodium]
GO:0033365 [protein localization to organelle]
GO:0036064 [ciliary basal body]
GO:0042384 [cilium assembly]
GO:0043547 [positive regulation of GTPase activity]
Show all
 254 aa
28.6 kDa 		No 0
RAB3IP-012
ENSP00000450355
ENST00000549760
F8VNX9 [Direct mapping]
Rab-3A-interacting protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 166 aa
17.9 kDa 		No 0
RAB3IP-014
ENSP00000448218
ENST00000550647
H0YI02 [Direct mapping]
Rab-3A-interacting protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 237 aa
26.7 kDa 		No 0
RAB3IP-015
ENSP00000448688
ENST00000547055
H0YI66 [Direct mapping]
Rab-3A-interacting protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 91 aa
10.3 kDa 		No 0
RAB3IP-016
ENSP00000432634
ENST00000526994
H0YD03 [Direct mapping]
Rab-3A-interacting protein
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   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 189 aa
21.3 kDa 		No 0
RAB3IP-017
ENSP00000448102
ENST00000550847
F8VTR6 [Direct mapping]
Rab-3A-interacting protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 167 aa
19.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.