Expression of LRRC61 in cancer - Summary - The Human Protein Atlas

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LRRC61

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	LRRC61
Gene description	Leucine rich repeat containing 61
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (HDLM-2, NTERA-2)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Ubiquitous nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA019355
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PROGNOSTIC SUMMARY
Prognostic marker in glioma (unfavourable) and stomach cancer (favourable).
Glioma p<0.001 Stomach cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA019355

GENE INFORMATION
Gene name	LRRC61 (HGNC Symbol)
Synonyms	FLJ31392, HSPC295, MGC3036
Description	Leucine rich repeat containing 61 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q36.1
Chromosome location (bp)	150322639 - 150338150
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000127399 (version 83.38)
Entrez gene	65999
UniProt	Q9BV99 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BV99
Antibodypedia	LRRC61 antibodies

PROTEIN BROWSER

LRRC61-001	LRRC61-002	LRRC61-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LRRC61-001 ENSP00000352642 ENST00000359623	Q9BV99 [Direct mapping] Leucine-rich repeat-containing protein 61 A0A090N7W5 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	259 aa 28 kDa	No	0
LRRC61-002 ENSP00000339047 ENST00000323078	Q9BV99 [Direct mapping] Leucine-rich repeat-containing protein 61 A0A090N7W5 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	259 aa 28 kDa	No	0
LRRC61-003 ENSP00000420560 ENST00000493307	Q9BV99 [Direct mapping] Leucine-rich repeat-containing protein 61 A0A090N7W5 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	259 aa 28 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.