Expression of STYXL1 in cancer - Summary - The Human Protein Atlas

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STYXL1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	STYXL1
Gene description	Serine/threonine/tyrosine interacting-like 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Mainly cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA050261
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable).
Urothelial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA050261

GENE INFORMATION
Gene name	STYXL1 (HGNC Symbol)
Synonyms	DUSP24, MK-STYX
Description	Serine/threonine/tyrosine interacting-like 1 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q11.23
Chromosome location (bp)	75996338 - 76048004
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000127952 (version 83.38)
Entrez gene	51657
UniProt	Q9Y6J8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9Y6J8
Antibodypedia	STYXL1 antibodies

PROTEIN BROWSER

STYXL1-001	STYXL1-002	STYXL1-003	STYXL1-005	STYXL1-009	STYXL1-201	STYXL1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STYXL1-001 ENSP00000352726 ENST00000359697	Q9Y6J8 [Direct mapping] Serine/threonine/tyrosine-interacting-like protein 1 A0A024R4L1 [Target identity:100%; Query identity:100%] Serine/threonine/tyrosine interacting-like 1, isoform CRA_c Show all	Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0006470 [protein dephosphorylation] GO:0008138 [protein tyrosine/serine/threonine phosphatase activity] GO:0035556 [intracellular signal transduction] Show all	313 aa 35.8 kDa	No	0
STYXL1-002 ENSP00000343383 ENST00000340062	Q9Y6J8 [Direct mapping] Serine/threonine/tyrosine-interacting-like protein 1 Show all	Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0006470 [protein dephosphorylation] GO:0008138 [protein tyrosine/serine/threonine phosphatase activity] GO:0035556 [intracellular signal transduction] Show all	217 aa 24.8 kDa	No	0
STYXL1-003 ENSP00000411812 ENST00000451157	C9J4H0 [Direct mapping] Serine/threonine/tyrosine-interacting-like protein 1 Show all	Predicted intracellular proteins Show all	GO:0006470 [protein dephosphorylation] GO:0008138 [protein tyrosine/serine/threonine phosphatase activity] Show all	282 aa 32.1 kDa	No	0
STYXL1-005 ENSP00000392221 ENST00000431581	Q9Y6J8 [Direct mapping] Serine/threonine/tyrosine-interacting-like protein 1 A0A024R4L1 [Target identity:100%; Query identity:100%] Serine/threonine/tyrosine interacting-like 1, isoform CRA_c Show all	Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0006470 [protein dephosphorylation] GO:0008138 [protein tyrosine/serine/threonine phosphatase activity] GO:0035556 [intracellular signal transduction] Show all	313 aa 35.8 kDa	No	0
STYXL1-009 ENSP00000406073 ENST00000454618	A0A0C4DG63 [Direct mapping] Serine/threonine/tyrosine-interacting-like protein 1 Show all	Predicted intracellular proteins Show all		221 aa 25.1 kDa	No	0
STYXL1-201 ENSP00000248600 ENST00000248600	Q9Y6J8 [Direct mapping] Serine/threonine/tyrosine-interacting-like protein 1 A0A024R4L1 [Target identity:100%; Query identity:100%] Serine/threonine/tyrosine interacting-like 1, isoform CRA_c Show all	Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0006470 [protein dephosphorylation] GO:0008138 [protein tyrosine/serine/threonine phosphatase activity] GO:0035556 [intracellular signal transduction] Show all	313 aa 35.8 kDa	No	0
STYXL1-202 ENSP00000353798 ENST00000360591	Q9Y6J8 [Direct mapping] Serine/threonine/tyrosine-interacting-like protein 1 Show all	Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0006470 [protein dephosphorylation] GO:0008138 [protein tyrosine/serine/threonine phosphatase activity] GO:0035556 [intracellular signal transduction] Show all	217 aa 24.8 kDa	No	0

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The Project

The Human Protein Atlas

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