Expression of APOL5 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

APOL5

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	APOL5
Gene description	Apolipoprotein L, 5
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (liver cancer)
HPA (cell line):	Cell line enriched (U-698)
HPA (normal tissue):	Not detected

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. No RNA expression data detected and pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA040968
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (liver cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA040968

GENE INFORMATION
Gene name	APOL5 (HGNC Symbol)
Synonyms	APOLV
Description	Apolipoprotein L, 5 (HGNC Symbol)
Entrez gene summary	This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. [provided by RefSeq, Jul 2008]
Chromosome	22
Cytoband	q12.3
Chromosome location (bp)	35717872 - 35729483
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000128313 (version 83.38)
Entrez gene	80831
UniProt	Q9BWW9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BWW9
Antibodypedia	APOL5 antibodies

PROTEIN BROWSER

APOL5-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
APOL5-001 ENSP00000249044 ENST00000249044	Q9BWW9 [Direct mapping] Apolipoprotein L5 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Show all	GO:0005575 [cellular_component] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0006629 [lipid metabolic process] GO:0006869 [lipid transport] GO:0008035 [high-density lipoprotein particle binding] GO:0008289 [lipid binding] GO:0042157 [lipoprotein metabolic process] Show all	433 aa 47 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.