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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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RIBC2
  • TISSUE

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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

RIBC2

Gene description

RIB43A domain with coiled-coils 2

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (SiHa)
HPA (normal tissue):Group enriched (fallopian tube, testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Mainly luminal cytoplasmic expression in fallopian tube and respiratory epithelia.

ANTIBODY IHC RELIABILITY

Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Reliability score

Uncertain based on 1 antibody.
HPA003210
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PROGNOSTIC SUMMARY

Prognostic marker in cervical cancer (favourable).
Cervical cancer p<0.001
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA003210

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Most cancer tissues were negative. In a few breast-, endometrial- and renal carcinomas, weak to moderate cytoplasmic or membranous immunoreactivity was observed.

GENE INFORMATION

Gene name

RIBC2 (HGNC Symbol)

Synonyms

C22orf11, DKFZp566F0546, FLJ25720

Description

RIB43A domain with coiled-coils 2 (HGNC Symbol)

Entrez gene summary

Chromosome

22

Cytoband

q13.31

Chromosome location (bp)

45413691 - 45432496

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000128408 (version 83.38)

Entrez gene

26150

UniProt

neXtProt

Antibodypedia

RIBC2 antibodies

PROTEIN BROWSER

RIBC2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RIBC2-001
ENSP00000483356
ENST00000614167
A0A087X0F7 [Direct mapping]
RIB43A domain with coiled-coils 2; RIB43A-like with coiled-coils protein 2
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Predicted intracellular proteins
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382 aa
45.4 kDa
No 0

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The Human Protein Atlas project is funded
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