Moderate to strong cytoplasmic positivity in subset of cancer cells in most endometrial cancers. Weak to moderate staining was displayed mainly in several colorectal and testis cancers and carcinoids. Remaining cancer tissues were negative.
VGF (HGNC Symbol)
VGF nerve growth factor inducible (HGNC Symbol)
Entrez gene summary
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008]
Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)