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Colorectal cancer along with several cases of ovarian and endometrial cancers showed moderate to strong membranous staining. Moderate membranous positivity was observed in several cases of breast, testicular, pancreatic and liver cancers. Remaining malignant cells were generally negative.
Q9HB65 [Direct mapping] RNA polymerase II elongation factor ELL3
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Predicted intracellular proteins Protein evidence (Kim et al 2014)
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GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0006354 [DNA-templated transcription, elongation] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006368 [transcription elongation from RNA polymerase II promoter] GO:0007283 [spermatogenesis] GO:0008023 [transcription elongation factor complex] GO:0010717 [regulation of epithelial to mesenchymal transition] GO:0032786 [positive regulation of DNA-templated transcription, elongation] GO:0035326 [enhancer binding] GO:0042795 [snRNA transcription from RNA polymerase II promoter] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048863 [stem cell differentiation] GO:0050769 [positive regulation of neurogenesis] GO:1901797 [negative regulation of signal transduction by p53 class mediator] GO:1902166 [negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator] GO:2000179 [positive regulation of neural precursor cell proliferation]