Expression of FAM63B in cancer - Summary - The Human Protein Atlas

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FAM63B

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM63B
Gene description	Family with sequence similarity 63, member B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic and nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA051103
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA051103

GENE INFORMATION
Gene name	FAM63B (HGNC Symbol)
Synonyms	KIAA1164
Description	Family with sequence similarity 63, member B (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband
Chromosome location (bp)	58771192 - 58861900
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000128923 (version 83.38)
Entrez gene	54629
UniProt	Q8NBR6 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NBR6
Antibodypedia	FAM63B antibodies

PROTEIN BROWSER

FAM63B-001	FAM63B-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM63B-001 ENSP00000452885 ENST00000559228	Q8NBR6 [Direct mapping] Protein FAM63B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005654 [nucleoplasm] GO:0008150 [biological_process] Show all	621 aa 67.1 kDa	No	0
FAM63B-004 ENSP00000393231 ENST00000450403	Q8NBR6 [Direct mapping] Protein FAM63B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005654 [nucleoplasm] GO:0008150 [biological_process] Show all	620 aa 67 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.