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MTUS1

GENERAL INFORMATION

Gene name

 MTUS1

Gene description

 Microtubule associated tumor suppressor 1

Protein class

 Disease related genes
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 8
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 MTUS1 (HGNC Symbol)

Synonyms

 ATBP, ATIP1, DKFZp586D1519, FLJ14295, ICIS, KIAA1288, MP44, MTSG1

Description

 Microtubule associated tumor suppressor 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]

Chromosome

 8

Cytoband

 p22

Chromosome location (bp)

 17643795 - 17800917

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000129422 (version 83.38)

Entrez gene

 57509

UniProt

 Q9ULD2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9ULD2

Antibodypedia

 MTUS1 antibodies

PROTEIN BROWSER
MTUS1-001
MTUS1-004
MTUS1-005
MTUS1-011
MTUS1-015
MTUS1-028
MTUS1-201
MTUS1-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MTUS1-001
ENSP00000262102
ENST00000262102
Q9ULD2 [Direct mapping]
Microtubule-associated tumor suppressor 1
Show all
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005739 [mitochondrion]
GO:0005794 [Golgi apparatus]
GO:0005815 [microtubule organizing center]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
Show all
 1270 aa
141.4 kDa 		No 0
MTUS1-004
ENSP00000430167
ENST00000519263
Q9ULD2 [Direct mapping]
Microtubule-associated tumor suppressor 1
Show all
Predicted intracellular proteins
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005739 [mitochondrion]
GO:0005794 [Golgi apparatus]
GO:0005815 [microtubule organizing center]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
Show all
 1216 aa
135.7 kDa 		No 0
MTUS1-005
ENSP00000297488
ENST00000297488
Q9ULD2 [Direct mapping]
Microtubule-associated tumor suppressor 1
Show all
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005739 [mitochondrion]
GO:0005794 [Golgi apparatus]
GO:0005815 [microtubule organizing center]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
Show all
 436 aa
50.5 kDa 		No 0
MTUS1-011
ENSP00000371285
ENST00000381861
Q9ULD2 [Direct mapping]
Microtubule-associated tumor suppressor 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005739 [mitochondrion]
GO:0005794 [Golgi apparatus]
GO:0005815 [microtubule organizing center]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
Show all
 517 aa
59 kDa 		No 1
MTUS1-015
ENSP00000489015
ENST00000519066
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 41 aa
4.5 kDa 		No 0
MTUS1-028
ENSP00000489288
ENST00000634613
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 342 aa
39.8 kDa 		No 0
MTUS1-201
ENSP00000371293
ENST00000381869
Q9ULD2 [Direct mapping]
Microtubule-associated tumor suppressor 1
Show all
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005739 [mitochondrion]
GO:0005794 [Golgi apparatus]
GO:0005815 [microtubule organizing center]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
Show all
 1216 aa
135.7 kDa 		No 0
MTUS1-202
ENSP00000445738
ENST00000544260
Q9ULD2 [Direct mapping]
Microtubule-associated tumor suppressor 1
Show all
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005739 [mitochondrion]
GO:0005794 [Golgi apparatus]
GO:0005815 [microtubule organizing center]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
Show all
 415 aa
48 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.