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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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AJUBA
  • TISSUE

  • CELL

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

AJUBA

Gene description

Ajuba LIM protein

Protein class

Cancer-related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

7
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (skin)
GTEx:Mixed
FANTOM5:Tissue enhanced (liver)

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression in several tissue types.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

Approved based on 1 antibody.
HPA006171
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
N/A
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
N/A
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Cervix, uterine

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (skin)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (liver)

GENE INFORMATION

Gene name

AJUBA (HGNC Symbol)

Synonyms

JUB, MGC15563

Description

Ajuba LIM protein (HGNC Symbol)

Entrez gene summary

Chromosome

14

Cytoband

q11.2

Chromosome location (bp)

22971174 - 22982642

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000129474 (version 83.38)

Entrez gene

84962

UniProt

Q96IF1 (UniProt - Evidence at protein level)

neXtProt

NX_Q96IF1

Antibodypedia

AJUBA antibodies

PROTEIN BROWSER

AJUBA-001
AJUBA-002
AJUBA-004
AJUBA-005
AJUBA-006
AJUBA-008
AJUBA-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AJUBA-001
ENSP00000262713
ENST00000262713
Q96IF1 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000278 [mitotic cell cycle]
GO:0000932 [cytoplasmic mRNA processing body]
GO:0001666 [response to hypoxia]
GO:0003682 [chromatin binding]
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005667 [transcription factor complex]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005925 [focal adhesion]
GO:0006351 [transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0016339 [calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules]
GO:0030027 [lamellipodium]
GO:0030032 [lamellipodium assembly]
GO:0030334 [regulation of cell migration]
GO:0031328 [positive regulation of cellular biosynthetic process]
GO:0031334 [positive regulation of protein complex assembly]
GO:0033673 [negative regulation of kinase activity]
GO:0033674 [positive regulation of kinase activity]
GO:0034613 [cellular protein localization]
GO:0035195 [gene silencing by miRNA]
GO:0035313 [wound healing, spreading of epidermal cells]
GO:0035331 [negative regulation of hippo signaling]
GO:0043087 [regulation of GTPase activity]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0045294 [alpha-catenin binding]
GO:0046474 [glycerophospholipid biosynthetic process]
GO:0048041 [focal adhesion assembly]
GO:0051015 [actin filament binding]
GO:1900037 [regulation of cellular response to hypoxia]
GO:2000637 [positive regulation of gene silencing by miRNA]
Show all
538 aa
56.9 kDa
No 0
AJUBA-002
ENSP00000380543
ENST00000397388
Q96IF1 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000278 [mitotic cell cycle]
GO:0000932 [cytoplasmic mRNA processing body]
GO:0001666 [response to hypoxia]
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0006351 [transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0031334 [positive regulation of protein complex assembly]
GO:0035195 [gene silencing by miRNA]
GO:0035331 [negative regulation of hippo signaling]
GO:0045294 [alpha-catenin binding]
GO:1900037 [regulation of cellular response to hypoxia]
GO:2000637 [positive regulation of gene silencing by miRNA]
Show all
121 aa
13.8 kDa
No 0
AJUBA-004
ENSP00000451772
ENST00000553736
H0YJL9 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
143 aa
14.8 kDa
No 0
AJUBA-005
ENSP00000451649
ENST00000556731
G3V481 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008270 [zinc ion binding]
Show all
80 aa
9.1 kDa
No 0
AJUBA-006
ENSP00000452325
ENST00000553911
G3V5F5 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008270 [zinc ion binding]
Show all
65 aa
7.2 kDa
No 0
AJUBA-008
ENSP00000452369
ENST00000553592
G3V481 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008270 [zinc ion binding]
Show all
80 aa
9.1 kDa
No 0
AJUBA-201
ENSP00000354491
ENST00000361265
Q96IF1 [Direct mapping]
LIM domain-containing protein ajuba
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000278 [mitotic cell cycle]
GO:0000932 [cytoplasmic mRNA processing body]
GO:0001666 [response to hypoxia]
GO:0003714 [transcription corepressor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0006351 [transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0031334 [positive regulation of protein complex assembly]
GO:0035195 [gene silencing by miRNA]
GO:0035331 [negative regulation of hippo signaling]
GO:0045294 [alpha-catenin binding]
GO:1900037 [regulation of cellular response to hypoxia]
GO:2000637 [positive regulation of gene silencing by miRNA]
Show all
538 aa
56.9 kDa
No 0

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