Expression of ABHD17A in cancer - Summary - The Human Protein Atlas

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ABHD17A

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ABHD17A
Gene description	Abhydrolase domain containing 17A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Avaliable gene/protein characterization data is inconclusive. External RNA data supports antibody staining.
Reliability score	Uncertain based on 2 antibodies. HPA043270 , HPA047226
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (favourable), endometrial cancer (favourable) and head and neck cancer (favourable).
Pancreatic cancer p<0.001 Endometrial cancer p<0.001 Head and neck cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043270	HPA047226

GENE INFORMATION
Gene name	ABHD17A (HGNC Symbol)
Synonyms	C19orf27, FAM108A1, MGC5244
Description	Abhydrolase domain containing 17A (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	1876810 - 1885547
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000129968 (version 83.38)
Entrez gene	81926
UniProt	Q96GS6 (UniProt - Evidence at protein level)
neXtProt	NX_Q96GS6
Antibodypedia	ABHD17A antibodies

PROTEIN BROWSER

ABHD17A-001	ABHD17A-002	ABHD17A-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABHD17A-001 ENSP00000292577 ENST00000292577	Q96GS6 [Direct mapping] Alpha/beta hydrolase domain-containing protein 17A Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016787 [hydrolase activity] Show all	310 aa 34 kDa	No	0
ABHD17A-002 ENSP00000250974 ENST00000250974	Q96GS6 [Direct mapping] Alpha/beta hydrolase domain-containing protein 17A Show all	MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016787 [hydrolase activity] Show all	361 aa 39.1 kDa	No	0
ABHD17A-003 ENSP00000467638 ENST00000590661	K7EQ25 [Direct mapping] Alpha/beta hydrolase domain-containing protein 17A Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		225 aa 24.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.