Expression of FAM155B in cancer - Summary - The Human Protein Atlas

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FAM155B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM155B
Gene description	Family with sequence similarity 155, member B
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (AN3-CA, NTERA-2, SCLC-21H)
HPA (normal tissue):	Tissue enhanced (heart muscle, seminal vesicle, thyroid gland)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA036093
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PROGNOSTIC SUMMARY
Prognostic marker in breast cancer (unfavourable), prostate cancer (unfavourable) and renal cancer (favourable).
Breast cancer p<0.001 Prostate cancer p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036093

GENE INFORMATION
Gene name	FAM155B (HGNC Symbol)
Synonyms	CXorf63, TED, TMEM28
Description	Family with sequence similarity 155, member B (HGNC Symbol)
Entrez gene summary	This gene encodes a product belonging to a family of proteins with unknown function. The presence of two transmembrane domains suggests that this protein is a multi-pass membrane protein. [provided by RefSeq, Sep 2011]
Chromosome	X
Cytoband	q13.1
Chromosome location (bp)	69505241 - 69532508
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000130054 (version 83.38)
Entrez gene	27112
UniProt	O75949 (UniProt - Evidence at transcript level)
neXtProt	NX_O75949
Antibodypedia	FAM155B antibodies

PROTEIN BROWSER

FAM155B-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM155B-001 ENSP00000252338 ENST00000252338	O75949 [Direct mapping] Transmembrane protein FAM155B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	472 aa 52.5 kDa	No	2

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.