Cell atlas - ATP8B3 - The Human Protein Atlas

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ATP8B3

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ATP8B3
Gene description	ATPase, aminophospholipid transporter, class I, type 8B, member 3
Protein class	Enzymes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (Karpas-707, U-266/70)
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (Karpas-707, U-266/70) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ATP8B3 (HGNC Symbol)
Synonyms	ATPIK
Description	ATPase, aminophospholipid transporter, class I, type 8B, member 3 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to the other. This gene encodes member 3 of phospholipid-transporting ATPase 8B; other members of this protein family are located on chromosomes 1, 15 and 18. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	1782075 - 1812276
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000130270 (version 83.38)
Entrez gene	148229
UniProt	O60423 (UniProt - Evidence at transcript level)
neXtProt	NX_O60423
Antibodypedia	ATP8B3 antibodies

PROTEIN BROWSER

ATP8B3-001	ATP8B3-002	ATP8B3-005	ATP8B3-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATP8B3-001 ENSP00000445204 ENST00000526092	F5H3R9 [Direct mapping] Phospholipid-transporting ATPase IK Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0007030 [Golgi organization] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] GO:0046872 [metal ion binding] Show all	562 aa 64 kDa	No	4
ATP8B3-002 ENSP00000311336 ENST00000310127	O60423 [Direct mapping] Phospholipid-transporting ATPase IK Show all	Enzymes ENZYME proteins Hydrolases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0001669 [acrosomal vesicle] GO:0002080 [acrosomal membrane] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0007030 [Golgi organization] GO:0007339 [binding of sperm to zona pellucida] GO:0008152 [metabolic process] GO:0015914 [phospholipid transport] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] GO:0046872 [metal ion binding] Show all	1300 aa 146.8 kDa	No	>9
ATP8B3-005 ENSP00000437115 ENST00000525591	O60423 [Direct mapping] Phospholipid-transporting ATPase IK Show all	Enzymes ENZYME proteins Hydrolases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0002080 [acrosomal membrane] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0007030 [Golgi organization] GO:0008152 [metabolic process] GO:0015914 [phospholipid transport] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] GO:0046872 [metal ion binding] Show all	1263 aa 143.7 kDa	No	>9
ATP8B3-009 ENSP00000465027 ENST00000587160	K7EJ52 [Direct mapping] Phospholipid-transporting ATPase IK Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0007030 [Golgi organization] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] Show all	205 aa 22.9 kDa	No	2

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.