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ACSBG2

GENERAL INFORMATION

Gene name

 ACSBG2

Gene description

 Acyl-CoA synthetase bubblegum family member 2

Protein class

 Enzymes
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in spermatozoa in testis.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA043421 , HPA051013
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA043421
HPA051013

GENE INFORMATION

Gene name

 ACSBG2 (HGNC Symbol)

Synonyms

 BGR, DKFZp434K1635, PRTD-NY3

Description

 Acyl-CoA synthetase bubblegum family member 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.3

Chromosome location (bp)

 6135247 - 6193094

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000130377 (version 83.38)

Entrez gene

 81616

UniProt

 Q5FVE4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5FVE4

Antibodypedia

 ACSBG2 antibodies

PROTEIN BROWSER
ACSBG2-001
ACSBG2-002
ACSBG2-003
ACSBG2-004
ACSBG2-005
ACSBG2-006
ACSBG2-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ACSBG2-001
ENSP00000466336
ENST00000588485
Q5FVE4 [Direct mapping]
Long-chain-fatty-acid--CoA ligase ACSBG2
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Enzymes
   ENZYME proteins
   Ligase
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0001676 [long-chain fatty acid metabolic process]
GO:0003824 [catalytic activity]
GO:0004467 [long-chain fatty acid-CoA ligase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0006631 [fatty acid metabolic process]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0019432 [triglyceride biosynthetic process]
GO:0030154 [cell differentiation]
GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0047617 [acyl-CoA hydrolase activity]
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 479 aa
53.5 kDa 		No 0
ACSBG2-002
ENSP00000465589
ENST00000586696
Q5FVE4 [Direct mapping]
Long-chain-fatty-acid--CoA ligase ACSBG2
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Enzymes
   ENZYME proteins
   Ligase
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
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GO:0001676 [long-chain fatty acid metabolic process]
GO:0003824 [catalytic activity]
GO:0004467 [long-chain fatty acid-CoA ligase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0006631 [fatty acid metabolic process]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0019432 [triglyceride biosynthetic process]
GO:0030154 [cell differentiation]
GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0047617 [acyl-CoA hydrolase activity]
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 666 aa
74.4 kDa 		No 1
ACSBG2-003
ENSP00000467755
ENST00000591403
Q5FVE4 [Direct mapping]
Long-chain-fatty-acid--CoA ligase ACSBG2
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Enzymes
   ENZYME proteins
   Ligase
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0001676 [long-chain fatty acid metabolic process]
GO:0003824 [catalytic activity]
GO:0004467 [long-chain fatty acid-CoA ligase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0006631 [fatty acid metabolic process]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0019432 [triglyceride biosynthetic process]
GO:0030154 [cell differentiation]
GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0047617 [acyl-CoA hydrolase activity]
Show all
 666 aa
74.4 kDa 		No 1
ACSBG2-004
ENSP00000468394
ENST00000591738
K7ERT0 [Direct mapping]
Long-chain-fatty-acid--CoA ligase ACSBG2
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   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
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GO:0003824 [catalytic activity]
GO:0008152 [metabolic process]
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 129 aa
14.4 kDa 		No 0
ACSBG2-005
ENSP00000468652
ENST00000589401
K7ESC8 [Direct mapping]
Long-chain-fatty-acid--CoA ligase ACSBG2
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Predicted intracellular proteins
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 76 aa
8.5 kDa 		No 0
ACSBG2-006
ENSP00000465870
ENST00000588722
K7EL11 [Direct mapping]
Long-chain-fatty-acid--CoA ligase ACSBG2
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
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GO:0003824 [catalytic activity]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
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 142 aa
15.7 kDa 		No 1
ACSBG2-007
ENSP00000464938
ENST00000588304
Q5FVE4 [Direct mapping]
Long-chain-fatty-acid--CoA ligase ACSBG2
Show all
Enzymes
   ENZYME proteins
   Ligase
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0001676 [long-chain fatty acid metabolic process]
GO:0003824 [catalytic activity]
GO:0004467 [long-chain fatty acid-CoA ligase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0006631 [fatty acid metabolic process]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0019432 [triglyceride biosynthetic process]
GO:0030154 [cell differentiation]
GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0047617 [acyl-CoA hydrolase activity]
Show all
 616 aa
68.8 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.