Cell atlas - CEP85 - The Human Protein Atlas

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CEP85

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Golgi apparatus
	Nucleoli

Human cell
	Cytosol
	Golgi Apparatus
	Nucleoli

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GENERAL INFORMATION
Gene name	CEP85
Gene description	Centrosomal protein 85kDa
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoli & cytosol. In addition localized to the Golgi apparatus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli (supported), Cytosol (supported)
Additional location	In addition localized to the Golgi apparatus (approved)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA028252
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoli & cytosol. In addition localized to the Golgi apparatus.

Main location

Nucleoli (supported), Cytosol (supported)

Additional location

Golgi apparatus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA028252	A-431	Nucleoli
			Golgi apparatus
			Cytosol
	HPA028252	U-2 OS	Nucleoli
	HPA028252	U-2 OS	Cytosol
	HPA028252	U-251 MG	Nucleoli
			Golgi apparatus
			Cytosol

GENE INFORMATION
Gene name	CEP85 (HGNC Symbol)
Synonyms	CCDC21, DKFZP434L0117
Description	Centrosomal protein 85kDa (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that belongs to the centrosome-associated family of proteins. The centrosome is a subcellular organelle in the animal cell that functions as a microtubule organizing center and is involved in cell-cycle progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Chromosome	1
Cytoband	p36.11
Chromosome location (bp)	26234153 - 26279038
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130695 (version 83.38)
Entrez gene	64793
UniProt	Q6P2H3 (UniProt - Evidence at protein level)
neXtProt	NX_Q6P2H3
Antibodypedia	CEP85 antibodies

PROTEIN BROWSER

CEP85-002	CEP85-003	CEP85-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CEP85-002 ENSP00000252992 ENST00000252992	Q6P2H3 [Direct mapping] Centrosomal protein of 85 kDa Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000922 [spindle pole] GO:0005515 [protein binding] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0005813 [centrosome] Show all	762 aa 85.6 kDa	No	0
CEP85-003 ENSP00000391790 ENST00000453146	H7BZW2 [Direct mapping] Centrosomal protein of 85 kDa Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005813 [centrosome] Show all	435 aa 50.2 kDa	No	0
CEP85-201 ENSP00000417002 ENST00000451429	Q6P2H3 [Direct mapping] Centrosomal protein of 85 kDa Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000922 [spindle pole] GO:0005515 [protein binding] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0005813 [centrosome] Show all	711 aa 80.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.