Expression of C19orf66 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

C19orf66

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C19orf66
Gene description	Chromosome 19 open reading frame 66
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA042001
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), urothelial cancer (favourable) and breast cancer (favourable).
Renal cancer p<0.001 Urothelial cancer p<0.001 Breast cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042001

GENE INFORMATION
Gene name	C19orf66 (HGNC Symbol)
Synonyms	FLJ11286
Description	Chromosome 19 open reading frame 66 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	10086122 - 10093252
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130813 (version 83.38)
Entrez gene	55337
UniProt	Q9NUL5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NUL5
Antibodypedia	C19orf66 antibodies

PROTEIN BROWSER

C19orf66-001	C19orf66-002	C19orf66-004	C19orf66-010	C19orf66-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C19orf66-001 ENSP00000253110 ENST00000253110	Q9NUL5 [Direct mapping] UPF0515 protein C19orf66 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	291 aa 33.1 kDa	No	0
C19orf66-002 ENSP00000467182 ENST00000591813	Q9NUL5 [Direct mapping] UPF0515 protein C19orf66 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	255 aa 29 kDa	No	0
C19orf66-004 ENSP00000380978 ENST00000397881	Q9NUL5 [Direct mapping] UPF0515 protein C19orf66 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	240 aa 27.5 kDa	No	0
C19orf66-010 ENSP00000466550 ENST00000590378	K7EML3 [Direct mapping] UPF0515 protein C19orf66 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		71 aa 8.1 kDa	No	0
C19orf66-011 ENSP00000467167 ENST00000593131	K7EP02 [Direct mapping] UPF0515 protein C19orf66 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		143 aa 14.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.