Tissue expression of PLXNA3 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PLXNA3
Gene description	Plexin A3
Protein class	Plasma proteins Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	PLXNA3 (HGNC Symbol)
Synonyms	6.3, Plxn3, PLXN4, SEX, XAP-6
Description	Plexin A3 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression. [provided by RefSeq, Aug 2013]
Chromosome	X
Cytoband	q28
Chromosome location (bp)	154458281 - 154477779
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130827 (version 83.38)
Entrez gene	55558
UniProt	P51805 (UniProt - Evidence at protein level)
neXtProt	NX_P51805
Antibodypedia	PLXNA3 antibodies

PROTEIN BROWSER

PLXNA3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PLXNA3-001 ENSP00000358696 ENST00000369682	P51805 [Direct mapping] Plexin-A3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002116 [semaphorin receptor complex] GO:0004888 [transmembrane signaling receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0007411 [axon guidance] GO:0016020 [membrane] GO:0017154 [semaphorin receptor activity] GO:0021612 [facial nerve structural organization] GO:0021637 [trigeminal nerve structural organization] GO:0021766 [hippocampus development] GO:0021785 [branchiomotor neuron axon guidance] GO:0021860 [pyramidal neuron development] GO:0030334 [regulation of cell migration] GO:0048841 [regulation of axon extension involved in axon guidance] GO:0048843 [negative regulation of axon extension involved in axon guidance] GO:0050919 [negative chemotaxis] GO:0051495 [positive regulation of cytoskeleton organization] GO:0071526 [semaphorin-plexin signaling pathway] GO:0097485 [neuron projection guidance] GO:1902287 [semaphorin-plexin signaling pathway involved in axon guidance] GO:1990138 [neuron projection extension] Show all	1871 aa 207.7 kDa	Yes	1