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The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Q86V15 [Direct mapping] Zinc finger protein castor homolog 1
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Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q86V15 [Direct mapping] Zinc finger protein castor homolog 1
Show all
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0043231 [intracellular membrane-bounded organelle] GO:0045665 [negative regulation of neuron differentiation] GO:0046872 [metal ion binding] GO:0060040 [retinal bipolar neuron differentiation] GO:0060223 [retinal rod cell fate commitment] GO:0060226 [negative regulation of retinal cone cell fate commitment] GO:1902870 [negative regulation of amacrine cell differentiation]
