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Several melanomas exhibited moderate cytoplasmic positivity. Other cancers tissues were negative.
GENE INFORMATION
Gene name
CCL25 (HGNC Symbol)
Synonyms
Ckb15, SCYA25, TECK
Description
Chemokine (C-C motif) ligand 25 (HGNC Symbol)
Entrez gene summary
This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]