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RAB11FIP4

GENERAL INFORMATION

Gene name

 RAB11FIP4

Gene description

 RAB11 family interacting protein 4 (class II)

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cerebral cortex)
GTEx:Mixed
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in testis.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA021595
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 RAB11FIP4 (HGNC Symbol)

Synonyms

 FLJ00131, KIAA1821, MGC11316, RAB11-FIP4

Description

 RAB11 family interacting protein 4 (class II) (HGNC Symbol)

Entrez gene summary

 Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP4 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Apr 2008]

Chromosome

 17

Cytoband

 q11.2

Chromosome location (bp)

 31391624 - 31538217

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000131242 (version 83.38)

Entrez gene

 84440

UniProt

 Q86YS3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q86YS3

Antibodypedia

 RAB11FIP4 antibodies

PROTEIN BROWSER
RAB11FIP4-001
RAB11FIP4-002
RAB11FIP4-006
RAB11FIP4-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RAB11FIP4-001
ENSP00000482620
ENST00000621161
Q86YS3 [Direct mapping]
Rab11 family-interacting protein 4
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000910 [cytokinesis]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005768 [endosome]
GO:0005813 [centrosome]
GO:0016032 [viral process]
GO:0017137 [Rab GTPase binding]
GO:0030139 [endocytic vesicle]
GO:0030306 [ADP-ribosylation factor binding]
GO:0030496 [midbody]
GO:0032154 [cleavage furrow]
GO:0032456 [endocytic recycling]
GO:0042803 [protein homodimerization activity]
GO:0055038 [recycling endosome membrane]
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 637 aa
71.9 kDa 		No 0
RAB11FIP4-002
ENSP00000378227
ENST00000394744
Q86YS3 [Direct mapping]
Rab11 family-interacting protein 4
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000910 [cytokinesis]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005768 [endosome]
GO:0005813 [centrosome]
GO:0016032 [viral process]
GO:0017137 [Rab GTPase binding]
GO:0030139 [endocytic vesicle]
GO:0030306 [ADP-ribosylation factor binding]
GO:0030496 [midbody]
GO:0032154 [cleavage furrow]
GO:0032456 [endocytic recycling]
GO:0042803 [protein homodimerization activity]
GO:0055038 [recycling endosome membrane]
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 535 aa
60.8 kDa 		No 0
RAB11FIP4-006
ENSP00000463206
ENST00000582009
J3QKR9 [Direct mapping]
Rab11 family-interacting protein 4
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005813 [centrosome]
GO:0032456 [endocytic recycling]
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 163 aa
17.5 kDa 		No 0
RAB11FIP4-007
ENSP00000465929
ENST00000583755
K7EL58 [Direct mapping]
Rab11 family-interacting protein 4
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005813 [centrosome]
GO:0032456 [endocytic recycling]
Show all
 126 aa
14.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.