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TUBG1

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GENERAL INFORMATION

Gene name

 TUBG1

Gene description

 Tubulin, gamma 1

Protein class

 Disease related genes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 TUBG1 (HGNC Symbol)

Synonyms

 TUBG, TUBGCP1

Description

 Tubulin, gamma 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009]

Chromosome

 17

Cytoband

 q21.2

Chromosome location (bp)

 42609676 - 42615234

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000131462 (version 83.38)

Entrez gene

 7283

UniProt

 P23258 (UniProt - Evidence at protein level)

neXtProt

 NX_P23258

Antibodypedia

 TUBG1 antibodies

PROTEIN BROWSER
TUBG1-001
TUBG1-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TUBG1-001
ENSP00000251413
ENST00000251413
P23258 [Direct mapping]
Tubulin gamma-1 chain
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Disease related genes
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000212 [meiotic spindle organization]
GO:0000226 [microtubule cytoskeleton organization]
GO:0000242 [pericentriolar material]
GO:0000278 [mitotic cell cycle]
GO:0000794 [condensed nuclear chromosome]
GO:0000930 [gamma-tubulin complex]
GO:0003924 [GTPase activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005827 [polar microtubule]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0005876 [spindle microtubule]
GO:0005881 [cytoplasmic microtubule]
GO:0005929 [cilium]
GO:0006996 [organelle organization]
GO:0007017 [microtubule-based process]
GO:0007020 [microtubule nucleation]
GO:0008152 [metabolic process]
GO:0031122 [cytoplasmic microtubule organization]
GO:0031252 [cell leading edge]
GO:0031513 [nonmotile primary cilium]
GO:0036064 [ciliary basal body]
GO:0043234 [protein complex]
GO:0045177 [apical part of cell]
GO:0051258 [protein polymerization]
GO:0055037 [recycling endosome]
Show all
 451 aa
51.2 kDa 		No 0
TUBG1-004
ENSP00000464867
ENST00000591509
K7EIS0 [Direct mapping]
Tubulin gamma chain
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000930 [gamma-tubulin complex]
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005874 [microtubule]
GO:0007017 [microtubule-based process]
GO:0007020 [microtubule nucleation]
GO:0008152 [metabolic process]
GO:0031122 [cytoplasmic microtubule organization]
Show all
 265 aa
29.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.