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BARX1

GENERAL INFORMATION

Gene name

 BARX1

Gene description

 BARX homeobox 1

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enhanced (stomach cancer)
HPA (cell line):Group enriched (AN3-CA, HMC-1, NTERA-2, THP-1)
HPA (normal tissue):Tissue enriched (stomach)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (unfavourable) and head and neck cancer (unfavourable).
Endometrial cancer p<0.001
Head and neck cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enhanced (stomach cancer)

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 BARX1

Synonyms

Description

 BARX homeobox 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. [provided by RefSeq, Jul 2008]

Chromosome

 9

Cytoband

 q22.32

Chromosome location (bp)

 93951622 - 93955372

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000131668 (version 83.38)

Entrez gene

 56033

UniProt

 Q9HBU1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9HBU1

Antibodypedia

 BARX1 antibodies

PROTEIN BROWSER
BARX1-001
BARX1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
BARX1-001
ENSP00000253968
ENST00000253968
Q9HBU1 [Direct mapping]
Homeobox protein BarH-like 1
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Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
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GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007267 [cell-cell signaling]
GO:0009888 [tissue development]
GO:0009952 [anterior/posterior pattern specification]
GO:0030178 [negative regulation of Wnt signaling pathway]
GO:0030855 [epithelial cell differentiation]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048513 [organ development]
GO:0048536 [spleen development]
GO:0048856 [anatomical structure development]
GO:0055123 [digestive system development]
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 254 aa
27.3 kDa 		No 0
BARX1-002
ENSP00000385613
ENST00000401724
Q9HBU1 [Direct mapping]
Homeobox protein BarH-like 1
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Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0009888 [tissue development]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048513 [organ development]
GO:0055123 [digestive system development]
Show all
 100 aa
11.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.