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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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ZCCHC9
  • TISSUE

  • CELL

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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

ZCCHC9

Gene description

Zinc finger, CCHC domain containing 9

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

Uncertain based on 1 antibody.
HPA038404
SHOW MORE

PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA038404

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

A majority of cancer cells showed moderate cytoplasmic positivity. A few cases of breast and prostate cancers were strongly stained. Lymphomas, gliomas, carcinoids and testicular cancers were in general negative.

GENE INFORMATION

Gene name

ZCCHC9 (HGNC Symbol)

Synonyms

DKFZp761J139, PPP1R41

Description

Zinc finger, CCHC domain containing 9 (HGNC Symbol)

Entrez gene summary

Chromosome

5

Cytoband

q14.1

Chromosome location (bp)

81301590 - 81313297

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131732 (version 83.38)

Entrez gene

84240

UniProt

Q8N567 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8N567

Antibodypedia

ZCCHC9 antibodies

PROTEIN BROWSER

ZCCHC9-001
ZCCHC9-002
ZCCHC9-003
ZCCHC9-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ZCCHC9-001
ENSP00000254037
ENST00000254037
Q8N567 [Direct mapping]
Zinc finger CCHC domain-containing protein 9
A0A024RAL5 [Target identity:100%; Query identity:100%]
Zinc finger, CCHC domain containing 9, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0005730 [nucleolus]
GO:0006351 [transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0010923 [negative regulation of phosphatase activity]
GO:0044822 [poly(A) RNA binding]
Show all
271 aa
30.5 kDa
No 0
ZCCHC9-002
ENSP00000385047
ENST00000407610
Q8N567 [Direct mapping]
Zinc finger CCHC domain-containing protein 9
A0A024RAL5 [Target identity:100%; Query identity:100%]
Zinc finger, CCHC domain containing 9, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0005730 [nucleolus]
GO:0006351 [transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0010923 [negative regulation of phosphatase activity]
GO:0044822 [poly(A) RNA binding]
Show all
271 aa
30.5 kDa
No 0
ZCCHC9-003
ENSP00000369546
ENST00000380199
Q8N567 [Direct mapping]
Zinc finger CCHC domain-containing protein 9
A0A024RAL5 [Target identity:100%; Query identity:100%]
Zinc finger, CCHC domain containing 9, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0005730 [nucleolus]
GO:0006351 [transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0010923 [negative regulation of phosphatase activity]
GO:0044822 [poly(A) RNA binding]
Show all
271 aa
30.5 kDa
No 0
ZCCHC9-004
ENSP00000412637
ENST00000438268
Q8N567 [Direct mapping]
Zinc finger CCHC domain-containing protein 9
A0A024RAL5 [Target identity:100%; Query identity:100%]
Zinc finger, CCHC domain containing 9, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0005730 [nucleolus]
GO:0006351 [transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0010923 [negative regulation of phosphatase activity]
GO:0044822 [poly(A) RNA binding]
Show all
271 aa
30.5 kDa
No 0

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