Expression of KHDRBS3 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

KHDRBS3

premium

TISSUE

premium

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	KHDRBS3
Gene description	KH domain containing, RNA binding, signal transduction associated 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Group enriched (cerebral cortex, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear expression with varying intensity in several cell types.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.
Reliability score	Supported based on 2 antibodies. HPA000275 , HPA000500
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA000275	HPA000500

GENE INFORMATION
Gene name	KHDRBS3 (HGNC Symbol)
Synonyms	Etle, etoile, SALP, SLM-2, SLM2, T-STAR
Description	KH domain containing, RNA binding, signal transduction associated 3 (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q24.23
Chromosome location (bp)	135457457 - 135656722
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000131773 (version 83.38)
Entrez gene	10656
UniProt	O75525 (UniProt - Evidence at protein level)
neXtProt	NX_O75525
Antibodypedia	KHDRBS3 antibodies

PROTEIN BROWSER

KHDRBS3-001	KHDRBS3-002	KHDRBS3-004	KHDRBS3-005	KHDRBS3-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KHDRBS3-001 ENSP00000348108 ENST00000355849	O75525 [Direct mapping] KH domain-containing, RNA-binding, signal transduction-associated protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007283 [spermatogenesis] GO:0017124 [SH3 domain binding] GO:0044822 [poly(A) RNA binding] Show all	346 aa 38.8 kDa	No	0
KHDRBS3-002 ENSP00000428607 ENST00000520981	E5RHD3 [Direct mapping] KH domain-containing, RNA-binding, signal transduction-associated protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		119 aa 13.8 kDa	No	0
KHDRBS3-004 ENSP00000430284 ENST00000517394	E5RG12 [Direct mapping] KH domain-containing, RNA-binding, signal transduction-associated protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] Show all	161 aa 18.4 kDa	No	0
KHDRBS3-005 ENSP00000431022 ENST00000524199	E5RJZ9 [Direct mapping] KH domain-containing, RNA-binding, signal transduction-associated protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005654 [nucleoplasm] Show all	265 aa 29.5 kDa	No	0
KHDRBS3-006 ENSP00000427841 ENST00000524282	H0YAQ1 [Direct mapping] KH domain-containing, RNA-binding, signal transduction-associated protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003723 [RNA binding] Show all	195 aa 21.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.