Cell atlas - RAI2 - The Human Protein Atlas

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RAI2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Plasma membrane

Human cell
	Plasma Membrane

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GENERAL INFORMATION
Gene name	RAI2
Gene description	Retinoic acid induced 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the plasma membrane.
RNA cell category	Cell line enhanced (EFO-21, ASC TERT1, RPTEC TERT1, HEK 293)
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA051054
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (EFO-21, ASC TERT1, RPTEC TERT1, HEK 293) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the plasma membrane.

Main location

Plasma membrane (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA051054	HEK 293	Plasma membrane
	HPA051054	U-2 OS	Plasma membrane

GENE INFORMATION
Gene name	RAI2
Synonyms
Description	Retinoic acid induced 2 (HGNC Symbol)
Entrez gene summary	Retinoic acid plays a critical role in development, cellular growth, and differentiation. The specific function of this retinoic acid-induced gene has not yet been determined but it may play a role in development. The chromosomal location of this gene designates it to be a candidate for diseases such as Nance-Horan syndrome, sensorineural deafness, non-specific X-linked mental retardation, oral-facial-digital syndrome, and Fried syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Chromosome	X
Cytoband	p22.13
Chromosome location (bp)	17800049 - 17861337
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000131831 (version 83.38)
Entrez gene	10742
UniProt	Q9Y5P3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y5P3
Antibodypedia	RAI2 antibodies

PROTEIN BROWSER

RAI2-001	RAI2-002	RAI2-003	RAI2-004	RAI2-201	RAI2-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RAI2-001 ENSP00000333456 ENST00000331511	Q9Y5P3 [Direct mapping] Retinoic acid-induced protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0009790 [embryo development] Show all	530 aa 57.2 kDa	No	0
RAI2-002 ENSP00000353106 ENST00000360011	Q9Y5P3 [Direct mapping] Retinoic acid-induced protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0009790 [embryo development] Show all	530 aa 57.2 kDa	No	0
RAI2-003 ENSP00000392578 ENST00000415486	Q9Y5P3 [Direct mapping] Retinoic acid-induced protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0009790 [embryo development] Show all	480 aa 52 kDa	No	0
RAI2-004 ENSP00000473562 ENST00000509491	R4GNA9 [Direct mapping] Retinoic acid-induced protein 2 Show all	Predicted intracellular proteins Show all		82 aa 8.8 kDa	No	0
RAI2-201 ENSP00000401323 ENST00000451717	Q9Y5P3 [Direct mapping] Retinoic acid-induced protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0009790 [embryo development] Show all	530 aa 57.2 kDa	No	0
RAI2-202 ENSP00000444210 ENST00000545871	Q9Y5P3 [Direct mapping] Retinoic acid-induced protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0009790 [embryo development] Show all	530 aa 57.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.