Cell atlas - CNGA4 - The Human Protein Atlas

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CNGA4

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CNGA4
Gene description	Cyclic nucleotide gated channel alpha 4
Protein class	Predicted intracellular proteins Predicted membrane proteins Voltage-gated ion channels
Predicted localization	Intracellular,Membrane
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CNGA4 (HGNC Symbol)
Synonyms	CNCA2, CNG5, CNGB2, OCNC2, OCNCb
Description	Cyclic nucleotide gated channel alpha 4 (HGNC Symbol)
Entrez gene summary	CNGA4 is a modulatory subunit of vertebrate cyclic nucleotide-gated membrane channels that transduce odorant signals (Munger et al., 2001 [PubMed 11739959]).[supplied by OMIM, Mar 2008]
Chromosome	11
Cytoband	p15.4
Chromosome location (bp)	6234765 - 6244429
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132259 (version 83.38)
Entrez gene	1262
UniProt	Q8IV77 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IV77
Antibodypedia	CNGA4 antibodies

PROTEIN BROWSER

CNGA4-001	CNGA4-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CNGA4-001 ENSP00000369268 ENST00000379936	Q8IV77 [Direct mapping] Cyclic nucleotide-gated cation channel alpha-4 Show all	Voltage-gated ion channels Cyclic Nucleotide-Regulated Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005216 [ion channel activity] GO:0005221 [intracellular cyclic nucleotide activated cation channel activity] GO:0005222 [intracellular cAMP activated cation channel activity] GO:0005223 [intracellular cGMP activated cation channel activity] GO:0005249 [voltage-gated potassium channel activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006811 [ion transport] GO:0006996 [organelle organization] GO:0007608 [sensory perception of smell] GO:0016020 [membrane] GO:0017071 [intracellular cyclic nucleotide activated cation channel complex] GO:0030552 [cAMP binding] GO:0030553 [cGMP binding] GO:0030660 [Golgi-associated vesicle membrane] GO:0042391 [regulation of membrane potential] GO:0043204 [perikaryon] GO:0050896 [response to stimulus] GO:0051290 [protein heterotetramerization] GO:0055085 [transmembrane transport] GO:0060170 [ciliary membrane] GO:0071805 [potassium ion transmembrane transport] Show all	575 aa 66 kDa	No	5
CNGA4-003 ENSP00000433399 ENST00000533426	B4DYQ8 [Direct mapping] Cyclic nucleotide-gated cation channel alpha-4; cDNA FLJ51400, highly similar to Cyclic nucleotide-gated ol factory channel subunit OCNC2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins SignalP predicted secreted proteins Predicted intracellular proteins Show all	GO:0005222 [intracellular cAMP activated cation channel activity] GO:0005223 [intracellular cGMP activated cation channel activity] GO:0005249 [voltage-gated potassium channel activity] GO:0005887 [integral component of plasma membrane] GO:0030553 [cGMP binding] GO:0042391 [regulation of membrane potential] GO:0071805 [potassium ion transmembrane transport] Show all	225 aa 25.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.