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Most cancer tissues displayed moderate to strong cytoplasmic immunoreactivity. Additional membranous staining was observed in several pancreatic cancers. Carcinoids and renal cancers along with several lymphomas were weakly stained or negative.
GENE INFORMATION
Gene name
TIMM10B (HGNC Symbol)
Synonyms
FXC1, TIM10B, Tim9b
Description
Translocase of inner mitochondrial membrane 10 homolog B (yeast) (HGNC Symbol)
Entrez gene summary
FXC1, or TIMM10B, belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM, Apr 2004]