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RBM38

GENERAL INFORMATION

Gene name

 RBM38

Gene description

 RNA binding motif protein 38

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
CAB017036
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PROGNOSTIC SUMMARY
Prognostic marker in cervical cancer (favourable), renal cancer (unfavourable) and thyroid cancer (favourable).
Cervical cancer p<0.001
Renal cancer p<0.001
Thyroid cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
CAB017036

GENE INFORMATION

Gene name

 RBM38 (HGNC Symbol)

Synonyms

 dJ800J21.2, HSRNASEB, RNPC1, seb4B, SEB4D

Description

 RNA binding motif protein 38 (HGNC Symbol)

Entrez gene summary

Chromosome

 20

Cytoband

 q13.31

Chromosome location (bp)

 57391407 - 57409333

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000132819 (version 83.38)

Entrez gene

 55544

UniProt

 Q9H0Z9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H0Z9

Antibodypedia

 RBM38 antibodies

PROTEIN BROWSER
RBM38-001
RBM38-002
RBM38-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RBM38-001
ENSP00000348538
ENST00000356208
Q9H0Z9 [Direct mapping]
RNA-binding protein 38
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003729 [mRNA binding]
GO:0003730 [mRNA 3'-UTR binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005829 [cytosol]
GO:0006397 [mRNA processing]
GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest]
GO:0006978 [DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator]
GO:0007049 [cell cycle]
GO:0007050 [cell cycle arrest]
GO:0008285 [negative regulation of cell proliferation]
GO:0008380 [RNA splicing]
GO:0010830 [regulation of myotube differentiation]
GO:0030154 [cell differentiation]
GO:0043484 [regulation of RNA splicing]
GO:0044822 [poly(A) RNA binding]
GO:0070935 [3'-UTR-mediated mRNA stabilization]
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 239 aa
25.5 kDa 		No 0
RBM38-002
ENSP00000360263
ENST00000371219
A6NG75 [Direct mapping]
RNA-binding protein 38
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
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 158 aa
16.8 kDa 		No 0
RBM38-004
ENSP00000407848
ENST00000440234
Q9H0Z9 [Direct mapping]
RNA-binding protein 38
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003729 [mRNA binding]
GO:0003730 [mRNA 3'-UTR binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005829 [cytosol]
GO:0006397 [mRNA processing]
GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest]
GO:0006978 [DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator]
GO:0007049 [cell cycle]
GO:0007050 [cell cycle arrest]
GO:0008285 [negative regulation of cell proliferation]
GO:0008380 [RNA splicing]
GO:0030154 [cell differentiation]
GO:0043484 [regulation of RNA splicing]
GO:0044822 [poly(A) RNA binding]
GO:0070935 [3'-UTR-mediated mRNA stabilization]
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 121 aa
12.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.