Expression of OSER1 in cancer - Summary - The Human Protein Atlas

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OSER1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	OSER1
Gene description	Oxidative stress responsive serine-rich 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA045125
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PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (unfavourable).
Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA045125

GENE INFORMATION
Gene name	OSER1 (HGNC Symbol)
Synonyms	C20orf111, dJ1183I21.1, HSPC207, Osr1, Perit1
Description	Oxidative stress responsive serine-rich 1 (HGNC Symbol)
Entrez gene summary
Chromosome	20
Cytoband	q13.12
Chromosome location (bp)	44196496 - 44210791
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132823 (version 83.38)
Entrez gene	51526
UniProt	Q9NX31 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NX31
Antibodypedia	OSER1 antibodies

PROTEIN BROWSER

OSER1-001	OSER1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OSER1-001 ENSP00000255174 ENST00000255174	Q9NX31 [Direct mapping] Oxidative stress-responsive serine-rich protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		292 aa 31.8 kDa	No	0
OSER1-002 ENSP00000362061 ENST00000372970	Q9NX31 [Direct mapping] Oxidative stress-responsive serine-rich protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0070301 [cellular response to hydrogen peroxide] Show all	292 aa 31.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.