We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Adaptor-related protein complex 3, beta 1 subunit (HGNC Symbol)
Entrez gene summary
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
MEMSAT3 predicted membrane proteins Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding] GO:0005765 [lysosomal membrane] GO:0005794 [Golgi apparatus] GO:0006622 [protein targeting to lysosome] GO:0006886 [intracellular protein transport] GO:0007596 [blood coagulation] GO:0008089 [anterograde axon cargo transport] GO:0016020 [membrane] GO:0016192 [vesicle-mediated transport] GO:0019882 [antigen processing and presentation] GO:0019903 [protein phosphatase binding] GO:0030117 [membrane coat] GO:0030123 [AP-3 adaptor complex] GO:0030131 [clathrin adaptor complex] GO:0030665 [clathrin-coated vesicle membrane] GO:0030742 [GTP-dependent protein binding] GO:0032438 [melanosome organization] GO:0048007 [antigen processing and presentation, exogenous lipid antigen via MHC class Ib] GO:0048490 [anterograde synaptic vesicle transport] GO:0051138 [positive regulation of NK T cell differentiation]
